SCI
20 April 2024
Treatment response biomarkers: working towards personalised radiotherapy for lung cancer
(Journal of Thoracic Oncology, IF: 20.4)
Ashley Horne, Ken Harada, Katherine D. Brown, Kevin Lee Min Chua, Fiona McDonald, Gareth Price, Paul Martin Putora, Dominic G. Rothwell, Corinne Faivre-Finn
CORRESPONDENCE TO: Ashley.horne3@nhs.net
Due to major advances in the field of radiation oncology, patients with lung cancer (LC) can now receive technically individualised radiotherapy treatments. However, in the era of precision oncology, radiotherapy-based treatment selection needs to be improved as many patients do not benefit or are not offered optimum therapies. Cost-effective robust biomarkers can address this knowledge gap and lead to individuals being offered more bespoke treatments leading to improved outcome. This narrative review discusses some of the current achievements and challenges in the realisation of personalised radiotherapy delivery in patients with LC.
由于放射肿瘤学领域的重大进展,患有肺癌(LC)的患者现在可以在技术上接受个性化放疗。然而,在精准肿瘤学时代,因为许多患者未能从治疗中受益或未获得最佳治疗方案,基于放疗的治疗选择需要改进。经济效益高的稳健生物标志物可以解决这一知识差距,并促使个体获得定制的治疗方案,从而改善治疗结果。这篇综述讨论了在实现肺癌患者个性化放疗方面当前的一些成就和挑战。
W212N4
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